The first United States Microgravity Laboratory (USML-1) provided scientific research in materials science, fluid dynamics, biotechnology, and combustion science in a weightless environment inside the Spacelab module. This photograph is a close-up view of the Glovebox in operation during the mission. The Spacelab Glovebox, provided by the European Space Agency, offers experimenters new capabilities to test and develop science procedures and technologies in microgravity. It enables crewmembers to handle, transfer, and otherwise manipulate materials in ways that are impractical in the open Spacelab. The facility is equipped with three doors: a central port through which experiments are placed in the Glovebox and two glovedoors on both sides with an attachment for gloves or adjustable cuffs and adapters for cameras. The Glovebox has an enclosed compartment that offers a clean working space and minimizes the contamination risks to both Spacelab and experiment samples. Although fluid containment and ease of cleanup are major benefits provided by the facility, it can also contain powders and bioparticles; toxic, irritating, or potentially infectious materials; and other debris produced during experiment operations. The facility is equipped with photographic/video capabilities and permits mounting a microscope. For the USML-1 mission, the Glovebox experiments fell into four basic categories: fluid dynamics, combustion science, crystal growth, and technology demonstration. The USML-1 flew aboard the STS-50 mission in June 1992.