São Paulo, Brazil, is pictured at approximately 3:54 a.m. local time

iss073e0120414 (May 19, 2025) --- São Paulo, Brazil, the South American nation's largest city with a population of about 11.9 million, and its surrounding suburbs including Guarulhos, with a population of about 1.29 million, are pictured at approximately 3:54 a.m. local time from the International Space Station as it orbited 265 miles above the Atlantic Ocean.