jsc2025e036195 (4/4/2025) --- A confocal microscope image shows a human cartilage cell, with its nucleus stained in blue, following delivery of Janus Base Nanoparticles (JBNp) and the subsequent release of bioactive mRNA (pink) that was translated into function protein (green). Biomimetic Fabrication of Multi-Functional DNA-Inspired Nanomaterials via Controlled Self-assembly in Space (DNA Nano Therapeutics-Mission 2) continues prior research on in-space manufacturing of nanomaterials that mimic DNA and have applications for vaccines and regenerative medicine. Image courtesy of University of Connecticut.