jsc2025e065391 (1/15/2025) --- A six-well BioCell, the hardware that holds samples for the International Space Station Microgravity Associated Bone Loss-B (MABL-B) investigation, which assesses how bone-forming stem cells respond to microgravity. Researchers are measuring gene expression changes and the secretion of signaling proteins that promote bone formation and increase bone loss. Results could provide insight into spaceflight-related bone loss and support development of treatments for bone loss caused by disease on Earth. Credit: Mayo Clinic