Agricultural fields spread out beyond NASA's DC-8 airborne science laboratory as it heads for landing at Air Force Plant 42 in Palmdale, Calif.

NASA's DC-8 airborne science laboratory banks low over the Dryden Aircraft Operations Facility at Air Force Plant 42 in Palmdale, Calif., upon arrival November 8, 2007.

DC-8 lifts off from Air Force Plant 42 in Palmdale, Calif., at sunset.

DC-8 lifts off from Air Force Plant 42 in Palmdale, Calif., at sunset.

DC-8 lifts off from Air Force Plant 42 in Palmdale, Calif.

DC-8 lifts off from Air Force Plant 42 in Palmdale, Calif., at sunset.

DC-8 lifts off from Air Force Plant 42 in Palmdale, Calif., at sunset.

DC-8 lifts off from Air Force Plant 42 in Palmdale, Calif., at sunset.

DC-8 lifts off from Air Force Plant 42 in Palmdale, Calif., at sunset.

DC-8 lifts off from Air Force Plant 42 in Palmdale, Calif.

DC-8 lifts off from Air Force Plant 42 in Palmdale, Calif., at sunset.

DC-8 lifts off from Air Force Plant 42 in Palmdale, Calif.

DC-8 lifts off from Air Force Plant 42 in Palmdale, Calif., at sunset.

DC-8 lifts off from Air Force Plant 42 in Palmdale, Calif., at sunset.

DC-8 lifts off from Air Force Plant 42 in Palmdale, Calif., at sunset.

DC-8 lifts off from Air Force Plant 42 in Palmdale, Calif.

DC-8 lifts off from Air Force Plant 42 in Palmdale, Calif., at sunset.

DC-8 lifts off from Air Force Plant 42 in Palmdale, Calif., at sunset.

DC-8 lifts off from Air Force Plant 42 in Palmdale, Calif.

DC-8 lifts off from Air Force Plant 42 in Palmdale, Calif., at sunset.

DC-8 lifts off from Air Force Plant 42 in Palmdale, Calif.

DC-8 lifts off from Air Force Plant 42 in Palmdale, Calif., at sunset.

DC-8 lifts off from Air Force Plant 42 in Palmdale, Calif., at sunset.

DC-8 lifts off from Air Force Plant 42 in Palmdale, Calif.

DC-8 lifts off from Air Force Plant 42 in Palmdale, Calif., at sunset.

DC-8 lifts off from Air Force Plant 42 in Palmdale, Calif.

NASA's DC-8 flying laboratory lifts off the runway at Air Force Plant 42 in Palmdale, Calif., on its first flight in the ARCTAS atmospheric science mission.

The DC-8 aircraft returned to NASA’s Armstrong Flight Research Center Building 703 in Palmdale, California, on April 1, 2024, after completing its final mission supporting Airborne and Satellite Investigation of Asian Air Quality (ASIA-AQ). The aircraft and crew were welcomed back with a celebratory water salute by the U.S. Air Force Plant 42 Fire Department.

The DC-8 aircraft returned to NASA’s Armstrong Flight Research Center Building 703 in Palmdale, California, on April 1, 2024, after completing its final mission supporting Airborne and Satellite Investigation of Asian Air Quality (ASIA-AQ). The aircraft and crew were welcomed back with a celebratory water salute by the U.S. Air Force Plant 42 Fire Department.

NASA African Monsoon Multidisciplinary Analyses (NAMMA) DC-8 deployment to Cape Verde, Sal island, Africa

NASA and Samaritan's Purse DC-8 aircrafts met on the ramp in front of NASA's Armstrong Flight Research Center Building 703.

NASA's DC-8 airborne science laboratory soars over the Dryden Flight Research Center upon its return to the center on Nov. 8, 2007.

NASA and Samaritan's Purse DC-8 aircrafts met on the ramp in front of NASA's Armstrong Flight Research Center Building 703.

NASA and Samaritan's Purse DC-8 aircrafts met on the ramp in front of NASA's Armstrong Flight Research Center Building 703.

NASA's DC-8 airborne science laboratory banks low over Rogers Dry Lake at Edwards Air Force upon its return to NASA Dryden Flight Research Center Nov. 8, 2007.

NASA's DC-8 airborne science laboratory is shadowed by a NASA F/A-18 chase plane during a flyover of the Dryden Aircraft Operations Facility in Palmdale, Calif.

NASA and Samaritan’s Purse DC-8 aircrafts met on the ramp in front of NASA’s Armstrong Flight Research Center Building 703.

NASA and Samaritan's Purse DC-8 aircrafts met on the ramp in front of NASA's Armstrong Flight Research Center Building 703.

NASA's DC-8 airborne science laboratory is shadowed by a NASA F/A-18 chase plane during a flyover of the Dryden Aircraft Operations Facility in Palmdale, Calif.

NASA's DC-8 airborne science laboratory has become the first science aircraft to be based at the Dryden Aircraft Operations Facility in Palmdale, Calif.

NASA’s DC-8 operations engineer, Nickelle “Nicki” Reid, left, embraces Katherine Ball, chemical engineering Ph.D. candidate at California Institute of Technology, after the DC-8 aircraft and crew return to NASA Armstrong’s Building 703 in Palmdale, California, on April 1, 2024, following the aircraft’s final mission in support of the Airborne and Satellite Investigation of Asian Air Quality (ASIA-AQ).

From left, Andy Barry, DC-8 pilot; Todd Renfro, flight navigator; and Adam Devalon, flight engineer, share smiles after the DC-8 aircraft and crew return to NASA’s Armstrong Flight Research Center Building 703 in Palmdale, California, on April 1, 2024, following the aircraft’s final mission in support of the Airborne and Satellite Investigation of Asian Air Quality (ASIA-AQ).

NASA’s Armstrong Flight Research Center Director Brad Flick smiles as members of the DC-8 team gather and exchange congratulations after the aircraft and crew return to NASA Armstrong’s Building 703 in Palmdale, California, on April 1, 2024, following the aircraft’s final mission in support of the Airborne and Satellite Investigation of Asian Air Quality (ASIA-AQ).

The DC-8 aircraft returns to the hangar at NASA’s Armstrong Flight Research Center Building 703 in Palmdale, California, on April 1, 2024, after completing its final mission supporting Airborne and Satellite Investigation of Asian Air Quality (ASIA-AQ).

From left, Wayne Ringelberg, chief pilot at NASA’s Armstrong Flight Research Center in Edwards, California, is welcomed by Michael Thomson, director of NASA Armstrong’s Science Mission Directorate, and Kirsten Boogaard, NASA’s DC-8 project manager, after the DC-8 aircraft and crew return to NASA Armstrong’s Building 703 in Palmdale, California, on April 1, 2024, following the aircraft’s final mission in support of the Airborne and Satellite Investigation of Asian Air Quality (ASIA-AQ).

Walter Klein, DC-8 navigator, exits the aircraft cabin and is welcomed with applause from a supportive team after the DC-8 aircraft and crew return to NASA’s Armstrong Flight Research Center Building 703 in Palmdale, California, on April 1, 2024, following the aircraft’s final mission in support of the Airborne and Satellite Investigation of Asian Air Quality (ASIA-AQ).

Kelly Jellison, avionics lead, and Tim Sandon, flight engineer, exit the DC-8 aircraft cabin and are welcomed with applause from a supportive team after the DC-8 aircraft and crew return to NASA’s Armstrong Flight Research Center Building 703 in Palmdale, California, on April 1, 2024, following the aircraft’s final mission in support of the Airborne and Satellite Investigation of Asian Air Quality (ASIA-AQ).

NASA DC-8 crew members Nickelle “Nicki” Reid, operations engineer, left, and Isac Mata, engineer technician, exchange in a heartfelt hug after the DC-8 aircraft and crew return to NASA Armstrong’s Building 703 in Palmdale, California, on April 1, 2024, following the aircraft’s final mission in support of the Airborne and Satellite Investigation of Asian Air Quality (ASIA-AQ). Smiling in the background is Michael Thomson, director of NASA Armstrong’s Science Mission Directorate.

The Space Shuttle Endeavour, atop NASA's 747 Shuttle Carrier Aircraft (SCA), taking off for the Kennedy Space Center shortly after its landing on 11 October 1994, at Edwards, California, to complete mission STS-68. Endeavour was being ferried from the Kennedy Space Center, Florida, to Air Force Plant 42, Palmdale, California, where it will undergo six months of inspections, modifications, and systems upgrades. The STS-68 11-day mission was devoted to radar imaging of Earth's geological features with the Space Radar Laboratory.

NASA's 747 Shuttle Carrier Aircraft No. 911, with the space shuttle orbiter Endeavour securely mounted atop its fuselage, taxies to the runway to begin the ferry flight from Rockwell's Plant 42 at Palmdale, California, where the orbiter was built, to the Kennedy Space Center, Florida. At Kennedy, the space vehicle was processed and launched on orbital mission STS-49, which landed at NASA's Ames-Dryden Flight Research Facility (later redesignated Dryden Flight Research Center), Edwards, California, 16 May 1992. NASA 911, the second modified 747 that went into service in November 1990, has special support struts atop the fuselage and internal strengthening to accommodate the added weight of the orbiters.