STS-41 crewmembers conduct Detailed Supplementary Objective (DSO) 0472 Intraocular Pressure on the middeck of Discovery, Orbiter Vehicle (OV) 103. Mission Specialist (MS) William M. Shepherd rests his head on the stowed treadmill while Pilot Robert D. Cabana, holding Shepherd's eye open, prepares to measure Shepherd's intraocular pressure using a tono pen (in his right hand). Objectives include: establishing a database of changes in intraocular pressures that can be used to evaluate crew health; validating ten degree head down bedrest as a model for cephalad fluid shifts in microgravity; facilitating the interpretation of data by providing a quantative measure of microgravity induced cephalad fluid shifts; and validating the tono pen as an effective tool for diagnostic and scientific data collection.

STS044-04-001 (24 Nov-1 Dec 1991) --- Astronauts F. Story Musgrave (right) and Mario Runco, Jr., mission specialists, team up for one of the biomedical Detailed Supplementary Objective (DSO) test on the eight-day flight, this one involving intraocular pressure.

STS053-02-007 (2 - 9 Dec 1992) --- Astronaut Robert D. Cabana, pilot, uses a tonometer to check the intraocular pressure of astronaut Michael R. U. (Rich) Clifford, mission specialist. The two are on the Space Shuttle Discovery's mid-deck. This test is one of the mission's Detailed Supplementary Objectives (DSO) 472. The purpose of this DSO is to establish a data base of changes in intraocular pressures that can be used to evaluate crew health.

ISS034-E-035949 (21 Jan. 2013) --- NASA astronaut Tom Marshburn (right), Expedition 34 flight engineer, performs a Tonometry eye exam on Canadian Space Agency astronaut Chris Hadfield, flight engineer, in the Columbus laboratory of the International Space Station. The purpose of this exam is to measure intraocular eye pressure.

ISS036-E-006520 (5 June 2013) --- NASA astronaut Karen Nyberg, Expedition 36 flight engineer, conducts an ocular health exam on herself in the Destiny laboratory of the Earth-orbiting International Space Station. NASA astronaut Chris Cassidy, flight engineer, nearby but out of frame, assisted in the testing, part of a suite of eye exams carried out over a two-day period on various crew members to gather information on intraocular pressure and eye anatomy.

ISS030-E-200591 (6 April 2012) --- In the International Space Station?s Destiny laboratory, NASA astronaut Dan Burbank (left), Expedition 30 commander, uses the Health Maintenance System Tonometry payload to perform an intraocular pressure test on NASA astronaut Don Pettit, flight engineer. The activity was supervised via live Ku-band video by medical ground personnel.