jsc2024e050836 (3/16/2022) --- Maturation of Vascularized Liver Tissue Construct in Zero Gravity (MVP Cell-07) examines the behavior in microgravity of bioprinted or engineered liver tissue constructs that contain blood vessels. The liver tissue constructs with a surface dimension of 1cm x 1cm x 1cm are bioprinted with a gyroid-shaped architecture with interconnected channels, allowing for uniform flow and surface shear stress that adequately covers the entire inner surfaces of cell-laden tissue constructs. The investigation sheds light on the formation of small blood vessels in engineered tissue. Image courtesy of Wake Forest Institute for Regenerative Medicine.

jsc2024e036956 (3/9/2023) --- The Multi-use Variable-g Platform (MVP) Cell Experiment Module is shown. Twelve of these modules run with each housing three sample conditions for the Maturation of Vascularized Liver Tissue Construct in Zero Gravity (MVP Cell-07) investigation. Image courtesy of Grant Vellinger, Redwire.

jsc2024e036957 (5/24/2024) --- Six modules configured in their Powered Carrier for ascent. The carrier helps perfuse media through the tissue while launched in a cold bag, maintaining approximately 37°C for the Maturation of Vascularized Liver Tissue Construct in Zero Gravity (MVP Cell-07) investigation. Image courtesy of Grant Vellinger, Redwire.

jsc2024e043915 (6/17/2024) --- Maturation of Vascularized Liver Tissue Construct in Zero Gravity (MVP Cell-07) examines the behavior in microgravity of bioprinted or engineered liver tissue constructs that contain blood vessels. This preflight image shows A) Bioprinted vascularized construct with a gyroid design consisting of interconnected channels. B) Bioprinted human liver tissue construct fabricated using a digital light projection (DLP) printer. C) The tissue construct-containing flow chamber is connected to a perfusion system. Data from this vascularized liver tissue construct helps support the development of clinically relevant organs on Earth. Image courtesy of the Wake Forest Institute for Regenerative Medicine.

jsc2024e036959 (8/13/2018) --- The Multi-use Variable-g Platform (MVP) can run with two different gravity conditions that range from microgravity to 2g Image courtesy of Grant Vellinger, Redwire.

jsc2024e036958 (7/26/2016) --- The Multi-use Variable-g Platform (MVP) facility houses up to 12 modules of science. Pictured in this front view are two installed consumable modules that are used for minor environmental control, such as desiccation, CO2control, and ethylene scrubbing. Power and data connectors are also visible to provide the ground control team with health and status of the unit. Image courtesy of Grant Vellinger, Redwire.

iss073e0606894 (Sept. 5, 2025) --- JAXA (Japan Aerospace Exploration Agency) astronaut and Expedition 73 Flight Engineer Kimiya Yui works on the Maturation of Vascularized Liver Tissue Construct in Zero Gravity (MVP Cell-07) investigation aboard the International Space Station. The experiment examines how bioprinted or engineered liver tissue constructs containing blood vessels printed on Earth develop in a microgravity environment. This research aims to advance space-based tissue production, potentially ensuring astronaut health on future missions and improving treatments for patients on Earth.