Marshall's 1992 Inventor of the Year demonstrates his multi-layer water window imaging x-ray microscope.

NASA Mars Exploration Rover Opportunity found this image of a meteorite. The science team used two tools on Opportunity arm, the microscopic imager and the alpha particle X-ray spectrometer, to inspect the rock texture and composition.

NASA Mars Exploration Rover Opportunity found and examined this meteorite. The science team used two tools on Opportunity arm, the microscopic imager and the alpha particle X-ray spectrometer, to inspect the rock texture and composition.

To the crystallographer, this may not be a diamond but it is just as priceless. A Lysozyme crystal grown in orbit looks great under a microscope, but the real test is X-ray crystallography. The colors are caused by polarizing filters. Proteins can form crystals generated by rows and columns of molecules that form up like soldiers on a parade ground. Shining X-rays through a crystal will produce a pattern of dots that can be decoded to reveal the arrangement of the atoms in the molecules making up the crystal. Like the troops in formation, uniformity and order are everything in X-ray crystallography. X-rays have much shorter wavelengths than visible light, so the best looking crystals under the microscope won't necessarily pass muster under the X-rays. In order to have crystals to use for X-ray diffraction studies, crystals need to be fairly large and well ordered. Scientists also need lots of crystals since exposure to air, the process of X-raying them, and other factors destroy them. Growing protein crystals in space has yielded striking results. Lysozyme's structure is well known and it has become a standard in many crystallization studies on Earth and in space.

NASA's three Great Observatories -- the Hubble Space Telescope, the SpitzerSpace Telescope, and the Chandra X-ray Observatory -- joined forces to probe theexpanding remains of a supernova, called Kepler's supernova remnant, first seen 400 years ago by sky watchers, including astronomer Johannes Kepler. The combined image unveils a bubble-shaped shroud of gas and dust that is 14light-years wide and is expanding at 4 million miles per hour (2,000 kilometersper second). Observations from each telescope highlight distinct features of thesupernova remnant, a fast-moving shell of iron-rich material from the explodedstar, surrounded by an expanding shock wave that is sweeping up interstellar gasand dust. Each color in this image represents a different region of the electromagneticspectrum, from X-rays to infrared light. These diverse colors are shown in thepanel of photographs below the composite image. The X-ray and infrared datacannot be seen with the human eye. By color-coding those data and combining themwith Hubble's visible-light view, astronomers are presenting a more completepicture of the supernova remnant. Visible-light images from the Hubble telescope (colored yellow) reveal where the supernova shock wave is slamming into the densest regions of surrounding gas.The bright glowing knots are dense clumps from instabilities that form behindthe shock wave. The Hubble data also show thin filaments of gas that look likerippled sheets seen edge-on. These filaments reveal where the shock wave isencountering lower-density, more uniform interstellar material. The Spitzer telescope shows microscopic dust particles (colored red) that havebeen heated by the supernova shock wave. The dust re-radiates the shock wave'senergy as infrared light. The Spitzer data are brightest in the regionssurrounding those seen in detail by the Hubble telescope. The Chandra X-ray data show regions of very hot gas, and extremely high-energyparticles. The hottest gas (higher-energy X-rays, colored blue) is locatedprimarily in the regions directly behind the shock front. These regions alsoshow up in the Hubble observations, and also align with the faint rim of glowingmaterial seen in the Spitzer data. The X-rays from the region on the lower left(colored blue) may be dominated by extremely high-energy electrons that wereproduced by the shock wave and are radiating at radio through X-ray wavelengthsas they spiral in the intensified magnetic field behind the shock front. CoolerX-ray gas (lower-energy X-rays, colored green) resides in a thick interior shelland marks the location of heated material expelled from the exploded star. Kepler's supernova, the last such object seen to explode in our Milky Waygalaxy, resides about 13,000 light-years away in the constellation Ophiuchus. The Chandra observations were taken in June 2000, the Hubble in August 2003;and the Spitzer in August 2004. http://photojournal.jpl.nasa.gov/catalog/PIA06907

The target beneath the tool turret at the end of the rover's robotic arm in this image from NASA's Mars Exploration Rover Opportunity is "Private John Potts." It lies high on the southern side of "Marathon Valley," which slices through the western rim of Endeavour Crater. The target's informal name refers to a member of the Lewis and Clark Expedition's Corps of Discovery. The image was taken by Opportunity's front hazard avoidance camera on Jan. 5, 2016, during the 4,248th Martian day, or sol, of the rover's work on Mars. This camera is mounted low on the rover and has a wide-angle lens. In this image, the microscopic imager on the turret is pointed downward. Opportunity's examination of this target also used the turret's rock abrasion tool for removing the surface crust and alpha particle X-ray spectrometer for identifying chemical elements in the rock. http://photojournal.jpl.nasa.gov/catalog/PIA20285

The primary purpose of the Spacelab-3 mission was to conduct materials science experiments in a stable low-gravity environment. In addition, the crew performed research in life sciences, fluid mechanics, atmospheric science, and astronomy. Spacelab-3 was equipped with several new minilabs, special facilities that would be used repeatedly on future flights. Two elaborate crystal growth furnaces, a life support and housing facility for small animals, and two types of apparatus for the study of fluids were evaluated on their inaugural flight. In this photograph, astronaut Don Lind observes the mercuric iodide growth experiment through a microscope at the vapor crystal growth furnace. The goals of this investigation were to grow near-perfect single crystals of mercuric iodide and to gain improved understanding of crystal growth by a vapor process. Mercuric iodide crystals have practical use as sensitive x-ray and gamma-ray detectors, and in portable detector devices for nuclear power plant monitoring, natural resource prospecting, biomedical applications in diagnosis and therapy, and in astronomical instruments. Managed by the Marshall Space Flight Center, Spacelab-3 (STS-51B) was launched aboard the Space Shuttle Orbiter Challenger on April 29, 1985.

Four hundred years ago, sky watchers, including the famous astronomer Johannes Kepler, best known as the discoverer of the laws of planetary motion, were startled by the sudden appearance of a new star in the western sky, rivaling the brilliance of the nearby planets. Modern astronomers, using NASA's three orbiting Great Observatories, are unraveling the mysteries of the expanding remains of Kepler's supernova, the last such object seen to explode in our Milky Way galaxy. When a new star appeared Oct. 9, 1604, observers could use only their eyes to study it. The telescope would not be invented for another four years. A team of modern astronomers has the combined abilities of NASA's Great Observatories, the Spritzer Space Telescope (SST), Hubble Space Telescope (HST), and Chandra X-Ray Observatory (CXO), to analyze the remains in infrared radiation, visible light, and X-rays. Visible-light images from Hubble's Advanced Camera for Surveys reveal where the supernova shock wave is slamming into the densest regions of surrounding gas. The astronomers used the SST to probe for material that radiates in infrared light, which shows heated microscopic dust particles that have been swept up by the supernova shock wave. The CXO data show regions of very hot gas. The combined image unveils a bubble-shaped shroud of gas and dust, 14 light-years wide and expanding at 4 million mph. There have been six known supernovas in our Milky Way over the past 1,000 years. Kepler's is the only one in which astronomers do not know what type of star exploded. By combining information from all three Great Observatories, astronomers may find the clues they need. Project management for both the HST and CXO programs is the responsibility of NASA’s Marshall Space Flight Center in Huntsville, Alabama.

This microscopic imager mosaic of the rock called "Diamond Jenness" was snapped on sol 177 before NASA's Mars Exploration Rover Opportunity ground into the surface with its rock abrasion tool, or "Rat." Opportunity has bored nearly a dozen holes into the inner walls of "Endurance Crater." On sols 177 and 178 (July 23 and July 24, 2004), the rover worked double-duty on Diamond Jenness. Surface debris and the bumpy shape of the rock resulted in a shallow and irregular hole, only about 2 millimeters (0.08 inch) deep. The final depth was not enough to remove all the bumps and leave a neat hole with a smooth floor. This extremely shallow depression was then examined by the rover's alpha particle X-ray spectrometer. On Sol 178, Opportunity's "robotic rodent" dined on Diamond Jenness once again, grinding almost an additional 5 millimeters (about 0.2 inch). The rover then applied its Moessbauer spectrometer to the deepened hole. This double dose of Diamond Jenness enabled the science team to examine the rock at varying layers. Results from those grindings are currently being analyzed. The image mosaic is about 6 centimeters (2.4 inches) across. http://photojournal.jpl.nasa.gov/catalog/PIA06748

This 2015 diagram shows components of the investigations payload for NASA's Mars 2020 rover mission. Mars 2020 will re-use the basic engineering of NASA's Mars Science Laboratory to send a different rover to Mars, with new objectives and instruments, launching in 2020. The rover will carry seven instruments to conduct its science and exploration technology investigations. They are: Mastcam-Z, an advanced camera system with panoramic and stereoscopic imaging capability and the ability to zoom. The instrument also will determine mineralogy of the Martian surface and assist with rover operations. The principal investigator is James Bell, Arizona State University in Tempe. SuperCam, an instrument that can provide imaging, chemical composition analysis, and mineralogy. The instrument will also be able to detect the presence of organic compounds in rocks and regolith from a distance. The principal investigator is Roger Wiens, Los Alamos National Laboratory, Los Alamos, New Mexico. This instrument also has a significant contribution from the Centre National d'Etudes Spatiales, Institut de Recherche en Astrophysique et Planétologie (CNES/IRAP) France. Planetary Instrument for X-ray Lithochemistry (PIXL), an X-ray fluorescence spectrometer that will also contain an imager with high resolution to determine the fine-scale elemental composition of Martian surface materials. PIXL will provide capabilities that permit more detailed detection and analysis of chemical elements than ever before. The principal investigator is Abigail Allwood, NASA's Jet Propulsion Laboratory, Pasadena, California. Scanning Habitable Environments with Raman & Luminescence for Organics and Chemicals (SHERLOC), a spectrometer that will provide fine-scale imaging and uses an ultraviolet (UV) laser to determine fine-scale mineralogy and detect organic compounds. SHERLOC will be the first UV Raman spectrometer to fly to the surface of Mars and will provide complementary measurements with other instruments in the payload. SHERLOC includes a high-resolution color camera for microscopic imaging of Mars' surface. The principal investigator is Luther Beegle, JPL. The Mars Oxygen ISRU Experiment (MOXIE), an exploration technology investigation that will produce oxygen from Martian atmospheric carbon dioxide. The principal investigator is Michael Hecht, Massachusetts Institute of Technology, Cambridge, Massachusetts. Mars Environmental Dynamics Analyzer (MEDA), a set of sensors that will provide measurements of temperature, wind speed and direction, pressure, relative humidity and dust size and shape. The principal investigator is Jose Rodriguez-Manfredi, Centro de Astrobiologia, Instituto Nacional de Tecnica Aeroespacial, Spain. The Radar Imager for Mars' Subsurface Experiment (RIMFAX), a ground-penetrating radar that will provide centimeter-scale resolution of the geologic structure of the subsurface. The principal investigator is Svein-Erik Hamran, the Norwegian Defence Research Establishment, Norway. http://photojournal.jpl.nasa.gov/catalog/PIA19672