Biological Test Laboratory, Sample Operations Area, Lunar Receiving Laboratory, bldg 37, Manned Spacecraft Center, Houston, Texas.
Biological Test Laboratory, Sample Operations Area
ZEISS COMPOUND MICROSCOPE WITH MONITOR & MELISSA KIRVEN-BROOKS.  Space Station Biological Research Project. (SSBRP)
ARC-1996-AC96-0394-5
iss034e065948 (3/11/2013) --- A view of the Biological Research In Canisters-17 - A and B actuation (BRIC-17). BRIC supports a variety of plant growth investigations which focus on the growth and development of cell cultures in microgravity. Specimens are preserved with a chemical fixative and returned to the ground for post-flight evaluation.
Biological Research In Canisters-17
iss034e065937 (3/11/2013) --- A view of the Biological Research In Canisters-17 - A and B actuation (BRIC-17). BRIC supports a variety of plant growth investigations which focus on the growth and development of cell cultures in microgravity. Specimens are preserved with a chemical fixative and returned to the ground for post-flight evaluation.
Biological Research In Canisters-17
iss034e065943 (3/11/2013) --- A view of the Biological Research In Canisters-17 - A and B actuation (BRIC-17). BRIC supports a variety of plant growth investigations which focus on the growth and development of cell cultures in microgravity. Specimens are preserved with a chemical fixative and returned to the ground for post-flight evaluation.
Biological Research In Canisters-17
iss034e065939 (3/11/2013) --- A view of the Biological Research In Canisters-17 - A and B actuation (BRIC-17). BRIC supports a variety of plant growth investigations which focus on the growth and development of cell cultures in microgravity. Specimens are preserved with a chemical fixative and returned to the ground for post-flight evaluation.
Biological Research In Canisters-17
STS085-333-013 (12 August 1997) --- Astronaut Curtis L. Brown, Jr., mission commander, performs Biological Research in Canisters (BRIC) operations on the mid-deck of the Space Shuttle Discovery on flight day six.
BRIC - Biological Research in Canisters 10
View of subject wearing Biological Isolation Garment (BIG) during a qualification test.
Subject wearing Biological Isolation Garment during qualification test
iss052e073846 (Aug. 25, 2017) --- NASA astronaut Jack Fischer installling the Biological Research In Canisters (BRIC) Light Emitting Diode (LED) for future BRIC-LED experiments.
Biological Research In Canisters Light Emitting Diode Installation
iss052e073850 (Aug. 25, 2017) --- NASA astronaut Jack Fischer installs hardware Biological Research In Canisters - Light Emitting Diode (BRIC-LED) for future experiments investigating seedling, microbial, or fungal growth.
Biological Research In Canisters Light Emitting Diode Installation
Dr. Ye Zhang, project scientist for the ISS Research Office at NASA’s Kennedy Space Center in Florida, demonstrates how biological samples are tested in a microgravity simulation device in the Microgravity Simulation Support Facility on Dec. 20, 2018.
Microgravity Simulation Lab
ISS034-E-023768 (7 Jan. 2013) --- Canadian Space Agency astronaut Chris Hadfield, Expedition 34 flight engineer, prepares to insert biological samples in the Minus Eighty Laboratory Freezer for ISS (MELFI-1) in the Kibo laboratory of the International Space Station.
Hadfield prepares to insert biological samples in the MELFI-1
ISS030-E-116878 (9 Feb. 2012) --- European Space Agency astronaut Andre Kuipers, Expedition 30 flight engineer, prepares to insert biological samples in the Minus Eighty Laboratory Freezer for ISS (MELFI-1) in the Kibo laboratory of the International Space Station.
Kuipers prepares to insert biological samples in the MELFI
iss052e079049 (Aug. 31, 2017) --- NASA astronaut Jack Fischer with four cansiters of the Biological Research in Canisters-22 (BRIC-22) experiment in the Japanese Experiment Module (JEM) Pressurized Module (JPM). BRIC-22 studies the stress response in plants by comparing 8 different variants of thale cress (Arabidopsis thaliana) in the microgravity environment.
Biological Research in Canisters-22 (BRIC-22)
ISS034-E-023771 (7 Jan. 2013) --- Canadian Space Agency astronaut Chris Hadfield, Expedition 34 flight engineer, prepares to insert biological samples in the Minus Eighty Laboratory Freezer for ISS (MELFI-1) in the Kibo laboratory of the International Space Station.
Hadfield prepares to insert biological samples in the MELFI-1
ISS032-E-011639 (2 Aug. 2012) --- NASA astronaut Sunita Williams, Expedition 32 flight engineer, prepares to insert biological samples in the Minus Eighty Laboratory Freezer for ISS-2 (MELFI-2) in the Destiny laboratory of the International Space Station.
FE Williams inserts Biological Samples into the MELFI-2
ISS030-E-116879 (9 Feb. 2012) --- European Space Agency astronaut Andre Kuipers, Expedition 30 flight engineer, prepares to insert biological samples in the Minus Eighty Laboratory Freezer for ISS (MELFI-1) in the Kibo laboratory of the International Space Station.
Kuipers prepares to insert biological samples in the MELFI
ISS034-E-026607 (7 Jan. 2013) --- NASA astronaut Tom Marshburn, Expedition 34 flight engineer, prepares to insert biological samples in the Minus Eighty Laboratory Freezer for ISS (MELFI-1) in the Kibo laboratory of the International Space Station.
Marshburn prepares to insert biological samples in the MELFI-1
View of Canadian Space Agency (CSA) Chris Hadfield,Expedition 34 Flight Engineer (FE),preparing to insert biological samples in the Minus Eighty Laboratory Freezer for International Space Station (ISS) - (MELFI-1),in the Japanese Experiment Module (JEM) Pressurized Module (JPM).  Photo was taken during Expedition 34.
Hadfield prepares to insert biological samples in the MELFI-1
ISS030-E-116886 (9 Feb. 2012) --- European Space Agency astronaut Andre Kuipers, Expedition 30 flight engineer, prepares to insert biological samples in the Minus Eighty Laboratory Freezer for ISS (MELFI-1) in the Kibo laboratory of the International Space Station.
Kuipers prepares to insert biological samples in the MELFI
ISS030-E-050864 (26 Jan. 2012) --- NASA astronaut Don Pettit, Expedition 30 flight engineer, prepares to insert biological samples in the Minus Eighty Laboratory Freezer for ISS (MELFI-1) in the Kibo laboratory of the International Space Station.
Pettit prepares to insert biological samples in the MELFI in the JPM
ISS034-E-023786 (7 Jan. 2013) --- Canadian Space Agency astronaut Chris Hadfield, Expedition 34 flight engineer, prepares to insert biological samples in the Minus Eighty Laboratory Freezer for ISS (MELFI-1) in the Kibo laboratory of the International Space Station. Russian cosmonaut Roman Romanenko, flight engineer, is visible near Hadfield.
Hadfield prepares to insert biological samples in the MELFI-1
iss065e094066 (6/9/2021) --- A close-up view of the a BRIC-24 Canister and actuator tool. Biological Research In Canisters-24 (BRIC-24) tests how space affects organelle contacts and vacuole fusion in plants, systems that may be important for plant gravity sensing and response. Vacuoles are organelles in plant cells that have important functions.
Biological Research In Canisters Transfer to BRIC-LED Facility
iss052e079058 (Aug. 31, 2017) --- NASA astronaut Jack Fischer actuating four cansiters of the Biological Research in Canisters-22 (BRIC-22) experiment in the Japanese Experiment Module (JEM) Pressurized Module (JPM). BRIC-22 studies the stress response in plants by comparing 8 different variants of thale cress (Arabidopsis thaliana) in the microgravity environment.
Biological Research in Canisters-22 (BRIC-22)
iss065e094062 (6/9/2021) --- A close-up view of the a BRIC-24 Canister and actuator tool. Biological Research In Canisters-24 (BRIC-24) tests how space affects organelle contacts and vacuole fusion in plants, systems that may be important for plant gravity sensing and response. Vacuoles are organelles in plant cells that have important functions.
Biological Research In Canisters Transfer to BRIC-LED Facility
iss052e079043 (Aug. 31, 2017) --- NASA astronaut Jack Fischer actuating four cansiters of the Biological Research in Canisters-22 (BRIC-22) experiment in the Japanese Experiment Module (JEM) Pressurized Module (JPM). BRIC-22 studies the stress response in plants by comparing 8 different variants of thale cress (Arabidopsis thaliana) in the microgravity environment.
Biological Research in Canisters-22 (BRIC-22)
ISS030-E-050849 (26 Jan. 2012) --- NASA astronaut Don Pettit, Expedition 30 flight engineer, prepares to insert biological samples in the Minus Eighty Laboratory Freezer for ISS (MELFI-1) in the Kibo laboratory of the International Space Station.
Pettit prepares to insert biological samples in the MELFI-1 in the JPM
iss073e0002477_alt (April 28, 2025) --- JAXA (Japan Aerospace Exploration Agency) astronaut and Expedition 73 Commander Takuya Onishi processes cassettes containing biological fluid samples for installation inside the Advanced Space Experiment Processor-4, a research facility that can be shipped back and forth from Earth to space, for a biotechnology study.
Astronaut Takuya Onishi processes cassettes containing biological fluid samples
iss073e0002467 (April 28, 2025) --- JAXA (Japan Aerospace Exploration Agency) astronaut and Expedition 73 Commander Takuya Onishi processes cassettes containing biological fluid samples for installation inside the Advanced Space Experiment Processor-4, a research facility that can be shipped back and forth from Earth to space, for a biotechnology study.
Astronaut Takuya Onishi processes cassettes containing biological fluid samples
ISS030-E-050848 (26 Jan. 2012) --- NASA astronaut Don Pettit, Expedition 30 flight engineer, prepares to insert biological samples in the Minus Eighty Laboratory Freezer for ISS (MELFI-1) in the Kibo laboratory of the International Space Station.
Pettit prepares to insert biological samples in the MELFI-1 in the JPM
Dr. Oliver Ullrich (left) from the University of Zurich and Dr. Howard Levine of NASA's Kennedy Space Center stood in the Space Station Processing Facility on Dec. 18, 2018. NASA recently signed a Space Act Agreement with the university, which is located in Switzerland, to collaborate on biological research. The team is studying gene expression in altered gravity.
Grip & Grin
From left to right: Dr. Oliver Ullrich from the University of Zurich, Dr. Ye Zhang and Dr. Howard Levine of NASA's Kennedy Space Center, and Dr. Cora Thiel of the University of Zurich stood in the Space Station Processing Facility on Dec. 18, 2018. NASA recently signed a Space Act Agreement with the university, which is located in Switzerland, to collaborate on biological research. The team is studying gene expression in altered gravity.
Grip & Grin
From left to right: Dr. Oliver Ullrich from the University of Zurich, Dr. Ye Zhang and Dr. Howard Levine of NASA's Kennedy Space Center, and Dr. Cora Thiel of the University of Zurich stood in the Space Station Processing Facility on Dec. 18, 2018. NASA recently signed a Space Act Agreement with the university, which is located in Switzerland, to collaborate on biological research. The team is studying gene expression in altered gravity.
Grip & Grin
Mary Kicza, NASA Associate Administrator for Biological and Physical Research.
Microgravity
SAC AND INCUBATOR WITH MELISSA KIRVEN-BROOKS.  Space Station Biological Research Project
ARC-1996-AC96-0394-2
Anthrax spores are inactive forms of Bacillus anthracis. They can survive for decades inside a spore's tough protective coating; they become active when inhaled by humans. A result of NASA- and industry-sponsored research to develop small greenhouses for space research is the unique AiroCide TiO2 system that kills anthrax spores and other pathogens.
Biotechnology
This graph based on data from the RAD instrument onboard NASA Mars Science Laboratory spacecraft shows the flux of energetic particles vertical axis as a function of the estimated energy deposited in water horizontal axis.
Calculating Radiation Dose for Biological Tissue
Khalid Alshibli of Louisiana State University, project scientist for the Mechanics of Granular Materials (MGM-III) experiment, explains the MGM experiment to Kristen Erickson, acting deputy associate administrator in NASA's Office of Biological and Physical Research. A training model of the test cell is at right. The activity was part of the Space Research and You education event held by NASA's Office of Biological and Physical Research on June 25, 2002, in Arlington, VA, to highlight the research that will be conducted on STS-107.
Material Science
Planetary protection engineers at NASA's Jet Propulsion Laboratory in Southern California swab engineering models of the tubes that will store Martian rock and sediment samples as part of NASA’s Mars 2020 Perseverance mission. Team members wanted to understand the transport of biological particles when the rover is taking rock cores. These measurements helped the rover team design hardware and sampling methods that meet stringent biological contamination control requirements.  https://photojournal.jpl.nasa.gov/catalog/PIA23718
Swabbing Perseverance Sample Tubes
iss060e043926 (Aug. 23, 2019) --- Expedition 60 Flight Engineer Christina Koch of NASA conducts science operations for the BioFabrication Facility experiment researching the effectiveness of using 3D biological printers to produce usable human organs in microgravity.
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DATE: 6-9-14 LOCATION: Bldg. 9, PDL (Life Sciences) SUBJECT: Instructors and crewmember Scott Kelly during Biological Sampling training session. PHOTOGRAPHER: Lauren Harnett
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DATE: 6-9-14 LOCATION: Bldg. 9, PDL (Life Sciences) SUBJECT: Instructors and crewmember Scott Kelly during Biological Sampling training session. PHOTOGRAPHER: Lauren Harnett
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DATE: 6-9-14 LOCATION: Bldg. 9, PDL (Life Sciences) SUBJECT: Instructors and crewmember Scott Kelly during Biological Sampling training session. PHOTOGRAPHER: Lauren Harnett
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DATE: 6-9-14 LOCATION: Bldg. 9, PDL (Life Sciences) SUBJECT: Instructors and crewmember Scott Kelly during Biological Sampling training session. PHOTOGRAPHER: Lauren Harnett
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iss063e104373 (Oct. 7, 2020) --- Roscosmos cosmonaut and Expedition 63 Flight Engineer Ivan Vagner transfers biological samples into a science freezer for stowage and later analysis aboard the International Space Station.
Vagner working with MELFI
iss064e020149 (Jan. 5, 2021) --- JAXA (Japan Aerospace Exploration Agency) astronaut Soichi Noguchi works inside the Kibo laboratory module servicing a science freezer that stores and preserves biological samples for later analysis.
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iss060e035160 (Aug. 12, 2019) --- Expedition 60 Flight Engineer Christina Koch of NASA conducts science operations inside Japan's Kibo laboratory module with a science freezer that preserves biological research samples for later analysis.
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iss064e016824 (Dec. 30, 2020) --- NASA astronaut Kate Rubins is pictured conducting science operations inside the portable glovebox to contain the accidental spillage of materials and prevent exposing the International Space Station's environment to biological samples.
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iss060e073348 (Sept. 18, 2019) --- NASA astronauts Christina Koch and Andrew Morgan stow biological research samples into a science freezer located inside the U.S. Destiny laboratory module.
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DATE: 6-9-14 LOCATION: Bldg. 9, PDL (Life Sciences) SUBJECT: Instructors and crewmember Scott Kelly during Biological Sampling training session. PHOTOGRAPHER: Lauren Harnett
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DATE: 6-9-14 LOCATION: Bldg. 9, PDL (Life Sciences) SUBJECT: Instructors and crewmember Scott Kelly during Biological Sampling training session. PHOTOGRAPHER: Lauren Harnett
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iss070e023971 (Nov. 13, 2023) --- NASA astronaut and Expedition 70 Flight Engineer Loral O'Hara uses a portable glovebag to replace components on a biological printer, the BioFabrication Facility (BFF), that is testing the printing of organ-like tissues in microgravity.
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iss064e024596 (Jan. 21, 2021) --- NASA astronaut and Expedition 64 Flight Engineer Shannon Walker inspects a science freezer that preserves biological samples for later analysis on Earth and on the International Space Station.
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iss054e001485 (Dec. 19, 2017) --- NASA astronaut Joe Acaba with Biological Research in Canisters - Light Emitting Diode (BRIC-LED) canisters prior to installation in the Destiny Laboratory to provide capabilities for seedling, microbial, or fungal growth investigations.
Acaba conducts BRIC-LED Experiment OPS
iss068e038127 (Jan. 5, 2023) --- NASA astronaut and Expedition 68 Flight Engineer Josh Cassada checks out and calibrates the mass measurement device that calculates the mass of biological research samples aboard the International Space Station.
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iss062e151901 (April 7, 2020) --- NASA astronaut Chris Cassidy services biological samples in a glovebag for the Food Physiology experiment to characterize the key effects of an enhanced spaceflight diet on immune function, the gut microbiome, and nutritional status indicators.
Food Physiology Fecal Portable Glovebag Hardware Replenish
iss054e001490 (Dec. 19, 2017) --- Biological Research in Canisters - Light Emitting Diode (BRIC-LED) locker installed in the Destiny Laboratory to provide capabilities for seedling, microbial, or fungal growth investigations.
BRIC-LED Experiment Canister Installation
A planetary protection engineer in full-body protective gear carefully collects samples from NASA's Europa Clipper spacecraft to verify its biological cleanliness in a clean room at NASA's Jet Propulsion Laboratory on March 20, 2024.  Maintaining and verifying the cleanliness of the spacecraft helps minimize the chance that microbes brought from Earth could compromise future scientific investigations at its destination, Jupiter's moon Europa. This work, referred to as planetary protection, is conducted in keeping with the international 1967 Outer Space Treaty to explore space in a responsible manner that avoids the harmful contamination of celestial bodies. This photo was taken while Europa Clipper was being built in JPL's Spacecraft Assembly Facility.  Europa Clipper's three main science objectives are to determine the thickness of the moon's icy shell and its interactions with the ocean below, to investigate its composition, and to characterize its geology. The mission's detailed exploration of Europa will help scientists better understand the astrobiological potential for habitable worlds beyond our planet.  https://photojournal.jpl.nasa.gov/catalog/PIA26440
Keeping Europa Clipper Clean
S86-27614 (Feb 1986) --- The Space Shuttle Columbia is at the center of the Spacelab   Life Sciences 1 patch.  The various elements of the logo serve to deliver the message of the dedication of this mission to medical and biological studies, a first for manned spaceflight.  A crew of five NASA astronauts and two payload specialists will be split into shifts to maximize the exposure to space environment for variegated and thorough biological and medical experiments during the scheduled ten-day mission.  The crew will maintain a constant communications link with scientists on Earth, considered by the flight crew to be an integral part of the overall mission, as well.
STS-1 - INSIGNIAS
iss051e036121 (5/3/2017) --- An over-the-shoulder look at Commander Peggy Whitson working inside the Microgravity Sciences Glovebox (MSG) to change the media in the BioCell for the OsteoOmics experiment. Image was taken in the Destiny U.S. Laboratory. Gravitational Regulation of Osteoblast Genomics and Metabolism (OsteoOmics) aims to validate if magnetic levitation is a reasonable simulation of orbital free fall by measuring biological endpoints, such as signaling pathways and gene expression in osteoblast and osteoclast cells.  Cells are exposed to a microgravity environment and ground based cells are exposed to magnetic levitation. If the validation is successful, then ground-based magnetic levitation will be an important ground-based tool to investigate the effect of gravitational force on biological systems.
Whitson conducts OsteoOmics OPS in MSG
iss051e036140 (5/3/2017) --- A view inside the Microgravity Sciences Glovebox (MSG) where Commander Peggy Whitson works to change the media in a BioCell for the OsteoOmics experiment. Image was taken in the Destiny U.S. Laboratory. Gravitational Regulation of Osteoblast Genomics and Metabolism (OsteoOmics) aims to validate if magnetic levitation is a reasonable simulation of orbital free fall by measuring biological endpoints, such as signaling pathways and gene expression in osteoblast and osteoclast cells. Cells are exposed to a microgravity environment and ground based cells are exposed to magnetic levitation. If the validation is successful, then ground-based magnetic levitation will be an important ground-based tool to investigate the effect of gravitational force on biological systems.
OsteoOmics OPS in MSG
iss065e094087 (6/9/2021) --- European Space Agency (ESA) astronaut Thomas Pesquet is photographed aboard the International Space Station (ISS) during transfers of BRIC-24 Canisters to BRIC-LED Facility to stow.
Biological Research In Canisters Transfer to BRIC-LED Facility
iss065e094086 (6/9/2021) --- European Space Agency (ESA) astronaut Thomas Pesquet is photographed aboard the International Space Station (ISS) during transfers of BRIC-24 Canisters to BRIC-LED Facility to stow.
Biological Research In Canisters Transfer to BRIC-LED Facility
While instruments on the pallets in the payload bay observed the universe, biological experiments were performed in the middeck of the Shuttle Orbiter Challenger. Studying life processes in a microgravity environment can shed new light on the functioning of biological systems on Earth. These investigations can also help us understand how living organisms react to prolonged weightlessness. One such experiment was the vitamin D metabolites and bone demineralization experiment. This investigation measured the vitamin D metabolite levels of crew members to gain information on the cause of bone demineralization and mineral imbalance that occur during prolonged spaceflight as well as on Earth. Research into the biochemical nature of vitamin D has shown that the D-metabolites play a major role in regulating the body's calcium and phosphorus levels. One major function of the most biologically active vitamin D metabolite is to regulate the amount of calcium absorbed from the diet and taken out of bones. This investigation had two phases. The first was the developmental phase, which included extensive testing before flight, and the second, or final phase, involved the postflight analysis of the crew's blood samples. This photograph shows astronaut Story Musgrave in the middeck of the Shuttle Orbiter Challenger, attending to the blood samples he collected from crew members for the experiment.
Spacelab
While instruments on the pallets in the payload bay observed the universe, biological experiments were performed in the middeck of the Shuttle Orbiter Challenger. Studying life processes in a microgravity environment can shed new light on the functioning of biological systems on Earth. These investigations can also help us understand how living organisms react to prolonged weightlessness. One such experiment was the vitamin D metabolites and bone demineralization experiment. This investigation measured the vitamin d metabolite levels of crew members to gain information on the cause of bone demineralization and mineral imbalance that occur during prolonged spaceflight as well as on Earth. Research into the biochemical nature of vitamin D has shown that the D-metabolites play a major role in regulating the body's calcium and phosphorus levels. One major function of the most biologically active vitamin D metabolite is to regulate the amount of calcium absorbed from the diet and taken out of bones. This investigation had two phases. The first was the developmental phase, which included extensive testing before flight, and the second, or final phase, involved the postflight analysis of the crew's blood samples. This photograph shows a blood draw test kit and centrifuge used for the experiment aboard the Spacelab-2. Marshall Space Flight Center had management responsibilities of all Spacelab missions.
Spacelab
ISS018-E-018995 (10 Jan. 2009) --- Astronaut Sandra Magnus, Expedition 18 flight engineer, works with the Lab-on-a-Chip Application Development-Portable Test System (LOCAD-PTS) experiment in the Destiny laboratory of the International Space Station. LOCAD-PTS is a handheld device for rapid detection of biological and chemical substances onboard the station.
ISS Expedition 18 Lab-On-a-Chip Applications Development (LOCAD) OPS
ISS024-E-012546 (26 Aug. 2010) --- NASA astronaut Tracy Caldwell Dyson, Expedition 24 flight engineer, prepares to insert biological samples in a dewar tray in the Minus Eighty Laboratory Freezer for ISS (MELFI-1) in the Kibo laboratory of the International Space Station.
Vascular Blood Collection stowage in MELFI
ISS038-E-006765 (21 Nov. 2013) --- In the International Space Station's Destiny laboratory, NASA astronaut Rick Mastracchio, Expedition 38 flight engineer, prepares to replace a dewar tray in the Minus Eighty Laboratory Freezer for ISS (MELFI) after inserting biological samples into the trays.
Mastracchio removing dewar tray from MELFI
jsc2021e037286 (5/21/2021) --- A preflight view of the SALI incubator. The Space Automated Lab Incubator (SALI) supports a wide variety of investigations in the life, physical, and material sciences, focusing on research on biological systems and processes. SALI accommodates multiple sample packs or habitats and also serves as back-up cold stowage.
PRO Imagery Submittal - SALI
ISS038-E-006757 (21 Nov. 2013) --- In the International Space Station's Destiny laboratory, NASA astronaut Rick Mastracchio, Expedition 38 flight engineer, removes a dewar tray from the Minus Eighty Laboratory Freezer for ISS (MELFI) in order to insert biological samples into the trays.
Mastracchio removing dewar tray from MELFI
iss038e024951 (1/5/2014) --- Japan Aerospace Exploration Agency (JAXA) Koichi Wakata strapped into his sleeping bag in his sleep station located in the Node 2. Circadian Rhythms investigates the role of synchronized circadian rhythms, or the “biological clock,” and how it changes during long-duration spaceflight.
Sleep Station in Node 2
ISS037-E-010711 (5 Oct. 2013) --- In the International Space Station’s Destiny laboratory, NASA astronaut Michael Hopkins, Expedition 37 flight engineer, removes a dewar tray from the Minus Eighty Laboratory Freezer for ISS (MELFI) in order to insert biological samples into the trays.
HRF Operations
ISS024-E-006697 (28 June 2010) --- NASA astronaut Doug Wheelock, Expedition 24 flight engineer, prepares to insert biological samples into trays in the Minus Eighty Laboratory Freezer for ISS-2 (MELFI-2) in the Destiny laboratory of the International Space Station.
MELFI Sample Insertion
KENNEDY SPACE CENTER, FLA. -  Kimberly Beck is a Controlled Biological Systems trainee in the Spaceflight and Life Sciences Training Program.  She is helping with growth studies supporting the WONDER (Water Offset Nutrient Delivery Experiment) flight payload, which is investigating hydroponic plant crop production in microgravity.
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jsc2021e037287 (5/21/2021) ---  A preflight view of the SALI incubator. The Space Automated Lab Incubator (SALI) supports a wide variety of investigations in the life, physical, and material sciences, focusing on research on biological systems and processes. SALI accommodates multiple sample packs or habitats and also serves as back-up cold stowage.e.
PRO Imagery Submittal - SALI
NASA Chief Scientist Shannon Lucid, a former astronaut, introduces Northern Virginia students to the research that will be conducted on the STS-107 mission. The activity was part of the Space Research and You education event held by NASA's Office of Biological and Physical Research on June 25, 2002, in Arlington, VA, to highlight the research that will be conducted on STS-107.
Space Shuttle Projects
iss064e013392 (December 19, 2020) --- NASA astronaut Kate Rubins works in a glove bag on the MVP Cell-06 study. The experiment develops a biological model to study the effects of spaceflight on musculoskeletal disease. This investigation could lead to drugs to prevent the progression of this disease.
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KENNEDY SPACE CENTER, FLA. -  Kimberly Beck, a college trainee in Controlled Biological Systems in the Spaceflight and Life Sciences Training Program, is helping with growth studies supporting payload development.  Behind her is part of the WONDER (Water Offset Nutrient Delivery Experiment) flight payload that is investigating hydroponic plant crop production in microgravity.
KSC-04pd1397
ISS018-E-039228 (10 March 2009) --- One of two Expedition 18 spacewalkers on March 10 provided this close-up image of the Expose-R experiment,  reinstalled a short while earlier on the outside of the Russian segment of the International Space Station.  The European experiment is equipped with three trays which contain a variety of biological samples.
Russian Extravehicular Activity (EVA) 21A EXPOSE-R
ISS018-E-044268 (28 March 2009) --- Japan Aerospace Exploration Agency (JAXA) astronaut Koichi Wakata, Expedition 18/19 flight engineer, works on an experiment at the Saibo biological experiment rack in the Kibo laboratory of the International Space Station.
DomeGene Sample Removal from Cell Biology Experiment Facility (CBEF)
ss062e151904 (April 16, 2020) --- NASA astronaut Chris Cassidy services biological samples in a glovebag aboard the International Space Station (ISS) for the Food Physiology experiment to characterize the key effects of an enhanced spaceflight diet on immune function, the gut microbiome, and nutritional status indicators.
Food Physiology Fecal Portable Glovebag Hardware Replenish
iss054e001472 (Dec. 19, 2017) --- NASA astronaut Joe Acaba with Biological Research in Canisters - Light Emitting Diode (BRIC-LED) canisters in the Destiny Laboratory prior to installation to provide capabilities for seedling, microbial, or fungal growth investigations. NASA astronaut Mark Vande Hei is visible in the background.
Acaba conducts BRIC-LED Experiment OPS
ISS024-E-006707 (28 June 2010) --- After inserting biological samples, NASA astronaut Doug Wheelock, Expedition 24 flight engineer, replaces a dewar tray in the Minus Eighty Laboratory Freezer for ISS-2 (MELFI-2) in the Destiny laboratory of the International Space Station.
MELFI Sample Insertion
NASA Headquarter's Office of Infrastructure and Administration, Environmental Management Division presents the annual Blue Marble Award to Ames Scientist Leslie Prufert-Bebout receives . Leslie Prufert-Bebout is a microbial ecologist who studies many different species of algea in natural biological communities.
ARC-2010-ACD10-0100-001
iss072e035693 (Oct. 11, 2024) --- NASA astronaut and Expedition 72 Flight Engineer Mike Barratt stows research samples in a science freezer, also known as the Minus Eighty-Degree Laboratory Freezer for ISS (MELFI). MELFI can preserve biological samples such as blood, microbes, plants, and more for retrieval and later analysis.
Astronaut Mike Barratt stows research samples in a science freezer
ISS024-E-006699 (28 June 2010) --- NASA astronaut Doug Wheelock, Expedition 24 flight engineer, prepares to insert biological samples into trays in the Minus Eighty Laboratory Freezer for ISS-2 (MELFI-2) in the Destiny laboratory of the International Space Station.
MELFI Sample Insertion
iss073e0118086 (May 29, 2025) --- NASA astronaut and Expedition 73 Flight Engineer Anne McClain works inside the Destiny laboratory module's Materials Science Research Rack and swaps filters inside the Kermit microscope. Kermit is an all-in-one fluorescence microscope system used to conduct biological, physical, and materials science research.
NASA astronaut Anne McClain swaps filters inside the Kermit microscope
iss065e423765 (9/27/2021) --- --- A view of the Symbiotic Leguminous Nitrogen Fixation CubeLab onboard the International Space Station (ISS). Nitrogen Fixation of Leguminous Species in MicroG (Symbiotic Leguminous Nitrogen Fixation) explores microgravity’s effects on the growth and development of Vigna unguiculata, a legume capable of biological nitrogen fixation.
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ISS031-E-143832 (25 June 2012) --- European Space Agency astronaut Andre Kuipers, Expedition 31 flight engineer, prepares to insert biological samples in the Minus Eighty Laboratory Freezer for ISS-2 (MELFI-2) in the Destiny laboratory of the International Space Station.
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iss062e102715 (3/19/2020) --- A view of the Symbiotic Leguminous Nitrogen Fixation CubeLab onboard the International Space Station (ISS). Nitrogen Fixation of Leguminous Species in MicroG (Symbiotic Leguminous Nitrogen Fixation) explores microgravity’s effects on the growth and development of Vigna unguiculata, a legume capable of biological nitrogen fixation.
Symbiotic Leguminous Nitrogen Fixation CubeLab
iss066e123191 (Jan. 20, 2022) --- NASA astronaut Engineer Raja Chari gathers items for the Rhodium Synthetic Cryptobiology experiment for packing inside the SpaceX Cargo Dragon resupply ship. Results from the biotechnology study could help create more rugged biological components and advance these technologies for use in space and in extreme environments on Earth.
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iss061e120287 (Jan. 6, 2020) --- NASA astronauts (from left) Jessica Meir and Christina Koch work inside the Kibo laboratory module collecting frozen biological samples for stowage inside the SpaceX Dragon resupply ship. Dragon parachuted to a splashdown in the Pacific Ocean the following day on Jan. 7, 2020.
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ISS018-E-039227 (10 March 2009) --- One of  two Expedition 18 spacewalkers on March 10 provided this close-up image of the Expose-R experiment, reinstalled a short while earlier on the outside of the Russian segment of the International Space Station. The European experiment is equipped with three trays which contain a variety of biological samples.
Russian Extravehicular Activity (EVA) 21A EXPOSE-R
ISS018-E-039226 (10 March 2009) --- One of two Expedition 18 spacewalkers on March 10 provided this close-up image of the Expose-R experiment, reinstalled a short while earlier on the outside of the Russian segment of the International Space Station.  The European experiment is equipped with three trays which contain a variety of biological samples.
Russian Extravehicular Activity (EVA) 21A EXPOSE-R
iss065e341636 (9/2/2021) --- A view of the  Genes in Space 8 Fluorescence Viewer floating in front of the Cupola module window aboard the International Space Station (ISS). Genes in Space-9 evaluates low-cost and portable BioBits cell-free technology as well as two biological sensors aboard the International Space Station (ISS).
Genes in Space 8
A Virginia student works with a bottle and its cap in a mockup of the Middeck Glovebox used by astronauts on a number of space shuttle research missions. The activity was part of the Space Research and You education event held by NASA's Office of Biological and Physical Research on June 25, 2002, in Arlington, VA, to highlight the research that will be conducted on STS-107.
Space Shuttle Projects
ISS024-E-007346 (2 July 2010) --- NASA astronauts Tracy Caldwell Dyson (background) and Shannon Walker, both Expedition 24 flight engineers, prepare to insert biological samples in a dewar tray in the Minus Eighty Laboratory Freezer for ISS (MELFI-1) in the Kibo laboratory of the International Space Station.
MELFI Sample Insertion
iss070e022606 (Nov. 12, 2023) --- ESA (European Space Agency) astronaut and Expedition 70 Commander Andreas Mogensen replaces computer hardware inside the Advanced Space Experiment Processor-2 (ADSEP-2) that can house and process samples for a variety of biological and physical science experiments.
iss070e022606
iss065e004334 (4/25/2021) --- A view of the TangoLab Facility with the Space Tango CubeLab for the Nitrogen Fixation of Leguminous Species in MicroG (Symbiotic Leguminous Nitrogen Fixation) investigation. Symbiotic Leguminous Nitrogen Fixation explores the effects of microgravity on the growth and development of legumes, plants capable of biological nitrogen fixation with symbiotic bacteria.
TangoLab S/N 001 Card Cube Locker Removal
Contributes to many transport and regulatory processes and has multifunctional binding properties which range form various metals, to fatty acids, hormones, and a wide spectrum of therapeutic drugs. The most abundant protein of the circulatory system. It binds and transports an incredible variety of biological and pharmaceutical ligands throughout the blood stream. Principal Investigator was Larry DeLucas.
Microgravity